Marco - macrophage receptor with collagenous structure Gene

Rattus norvegicus

Gene ID: 367391 | Gene type: protein coding

About Marco

Summary

Enables G protein-coupled receptor binding activity; amyloid-beta binding activity; and cargo receptor activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; endocytosis; and positive regulation of ERK1 and ERK2 cascade. Located in cytoplasm and plasma membrane. Used to study silicosis. Biomarker of meningococcal meningitis. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human MARCO (macrophage receptor with collagenous structure). [provided by Alliance of Genome Resources, Apr 2022]

Marco Products(1)

mRNA	Protein	Name
NM_001109011.2	NP_001102481.1	macrophage receptor MARCO

Protein Preferred Names

Protein Names

macrophage receptor MARCO

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08147	MARCO Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17553	Marco Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24011	Marco Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Marco	NCBI	NCBI:8685
Macaca fascicularis	Marco	NCBI	NCBI:102137861
Mus musculus	Marco	NCBI	NCBI:17167

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