1. Gene
  2. Cpn1 - carboxypeptidase N subunit 1 Gene

Cpn1 - carboxypeptidase N subunit 1 Gene

Rattus norvegicus

Also known as Cpn

Gene ID: 365466 | Gene type: protein coding

About Cpn1

Summary

Enables Carboxypeptidase activity. Involved in bradykinin catabolic process; proteolysis; and response to glucocorticoid. Located in extracellular space. Human ortholog(s) of this gene implicated in Carboxypeptidase N deficiency. Orthologous to human CPN1 (Carboxypeptidase N subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Cpn1 Products(1)

mRNA Protein Name
NM_053526.2 NP_445978.1 carboxypeptidase N catalytic chain precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables carboxypeptidase activity IDA
IDA: Inferred from direct assay
11021404 RGD
enables carboxypeptidase activity IMP
IMP: Inferred from mutant phenotype
11299220 RGD
Biological Process GO Annotation Evidence Reference Source
involved in bradykinin catabolic process IMP
IMP: Inferred from mutant phenotype
11299220 RGD
involved in protein catabolic process IDA
IDA: Inferred from direct assay
11021404 RGD
involved in response to glucocorticoid IDA
IDA: Inferred from direct assay
10485340 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
10485340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carboxypeptidase N catalytic chain

carboxypeptidase N catalytic chain-like

carboxypeptidase N small subunit

carboxypeptidase N, polypeptide 1, 50kD

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpn1 NCBI NCBI:1369
Mus musculus Cpn1 NCBI NCBI:93721