2. Gene
  3. Tnfrsf10b - TNF receptor superfamily member 10b Gene

Tnfrsf10b - TNF receptor superfamily member 10b Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 364420 | Gene type: protein coding

About Tnfrsf10b

Summary

Predicted to enable identical protein binding activity and protease binding activity. Involved in extrinsic apoptotic signaling pathway via death domain receptors; male gonad development; and response to organic cyclic compound. Located in membrane. Biomarker of colon Cancer and osteoarthritis. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic Cancer (multiple); and urinary bladder Cancer. Orthologous to human TNFRSF10A (TNF Receptor Superfamily member 10a). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf10b Products(1)

mRNA Protein Name
NM_001395720.1 NP_001382649.1 TNF receptor superfamily member 10b precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: Inferred from mutant phenotype
19934367 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
12021051 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TNF receptor superfamily member 10b

tumor necrosis factor receptor superfamily, member 10b

Related Agents

Clinical Phase
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99260 Conatumumab Agonist 98.90% Phase 2
HY-P990715 Ozekibart 99.63% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14796 TNFRSF10B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17570 Tnfrsf10b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24030 Tnfrsf10b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990901 Aplitabart Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf10b NCBI NCBI:8795
Macaca fascicularis Tnfrsf10b NCBI NCBI:102133727
Mus musculus Tnfrsf10b NCBI NCBI:21933