2. Gene
  3. Polr2a - RNA polymerase II subunit A Gene

Polr2a - RNA polymerase II subunit A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rpo2-1

Gene ID: 363633 | Gene type: protein coding

About Polr2a

Summary

Predicted to enable several functions, including enzyme binding activity; promoter-specific chromatin binding activity; and protein C-terminus binding activity. Predicted to contribute to RNA polymerase II activity. Involved in cellular response to oxygen levels and response to organic cyclic compound. Located in nucleus. Orthologous to human POLR2A (RNA polymerase II subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr2a Products(3)

mRNA Protein Name
XM_039087313.1 XP_038943241.1 DNA-directed RNA polymerase II subunit RPB1 isoform X3
XM_343922.8 XP_343923.3 DNA-directed RNA polymerase II subunit RPB1 isoform X1
XM_039087312.1 XP_038943240.1 DNA-directed RNA polymerase II subunit RPB1 isoform X2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to oxygen levels IEP
IEP: Inferred from expression pattern
19095046 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
23026235 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase II subunit RPB1

Polymerase (RNA II (DNA directed), large polypeptide

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

polymerase (RNA) II subunit A

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135646 Eleutheroside B1 Inhibitor 98.73% Unkown
HY-RS10842 POLR2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19802 Polr2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26298 Polr2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr2a NCBI NCBI:5430