2. Gene
  3. Havcr2 - hepatitis A virus cellular receptor 2 Gene

Havcr2 - hepatitis A virus cellular receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as tim3

Gene ID: 363578 | Gene type: protein coding

About Havcr2

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and Toll-like Receptor signaling pathway. Located in cell surface. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Havcr2 Products(1)

mRNA Protein Name
NM_001100762.1 NP_001094232.1 hepatitis A virus cellular receptor 2 homolog precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
24508263 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatitis A virus cellular receptor 2 homolog

HAVcr-2

T cell immunoglobulin mucin-3

T-cell immunoglobulin and mucin domain-containing protein 3

T-cell immunoglobulin mucin receptor 3

T-cell membrane protein 3

TIM-3

TIMD-3

Related Agents

Clinical Phase
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P990085 Verzistobart Inhibitor / Phase 2
HY-P990701 Lomvastomig / Phase 2
HY-P990716 Sabestomig / Phase 1
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06022 HAVCR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17115 Havcr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23560 Havcr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991395 TQB2618 Inhibitor / Unkown
HY-P991396 LY-3321367 Inhibitor / Unkown
HY-P991397 Sym023 Inhibitor / Unkown
HY-P991449 LY3415244 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Havcr2 NCBI NCBI:84868
Canis familiaris Havcr2 NCBI NCBI:479318
Macaca fascicularis Havcr2 NCBI NCBI:102141722
Mus musculus Havcr2 NCBI NCBI:171285