2. Gene
  3. Sin3a - SIN3 transcription regulator family member A Gene

Sin3a - SIN3 transcription regulator family member A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 363067 | Gene type: protein coding

About Sin3a

Summary

Enables RNA binding activity. Involved in several processes, including aging; cellular response to dopamine; and regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Located in chromatin. Part of protein-containing complex. Used to study transient cerebral ischemia. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A). [provided by Alliance of Genome Resources, Apr 2022]

Sin3a Products(1)

mRNA Protein Name
NM_001395640.1 NP_001382569.1 paired amphipathic helix protein Sin3a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IDA
IDA: Inferred from direct assay
24063527 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16776654 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
10491605 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to dopamine IEP
IEP: Inferred from expression pattern
15731170 RGD
involved in cellular response to tert-butyl hydroperoxide IDA
IDA: Inferred from direct assay
18945670 RGD
involved in regulation of hormone levels IMP
IMP: Inferred from mutant phenotype
15731170 RGD
Cellular Component GO Annotation Evidence Reference Source
located in chromatin IDA
IDA: Inferred from direct assay
16776654 RGD
located in nucleus IDA
IDA: Inferred from direct assay
18945670 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
10491605 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired amphipathic helix protein Sin3a

SIN3 homolog A, transcription regulator

SIN3 transcription regulator homolog A

transcriptional regulator, SIN3A

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P3242 Mad1 (6-21) 98.02% Unkown
HY-RS12925 SIN3A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-P3242A Mad1 (6-21) TFA / Unkown
HY-RS20104 Sin3a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26607 Sin3a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sin3a NCBI NCBI:25942