2. Gene
  3. Pias4 - protein inhibitor of activated STAT, 4 Gene

Pias4 - protein inhibitor of activated STAT, 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362827 | Gene type: protein coding

About Pias4

Summary

Enables protein C-terminus binding activity. Predicted to be involved in several processes, including positive regulation of keratinocyte apoptotic process; positive regulation of protein sumoylation; and regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; negative regulation of tumor necrosis factor-mediated signaling pathway; and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm; nuclear matrix; and nucleoplasm. Predicted to be part of transferase complex. Orthologous to human PIAS4 (protein inhibitor of activated STAT 4). [provided by Alliance of Genome Resources, Apr 2022]

Pias4 Products(1)

mRNA Protein Name
NM_001100757.1 NP_001094227.1 E3 SUMO-protein ligase PIAS4
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16144832 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 SUMO-protein ligase PIAS4

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114366 BC-1485 Inhibitor / Unkown
HY-RS10476 PIAS4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21021 Pias4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27538 Pias4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pias4 NCBI NCBI:51588