2. Gene
  3. Vrk1 - VRK serine/threonine kinase 1 Gene

Vrk1 - VRK serine/threonine kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362779 | Gene type: protein coding

About Vrk1

Summary

Predicted to enable histone kinase activity; nucleosomal histone binding activity; and protein kinase binding activity. Predicted to be involved in Golgi disassembly; histone H3-S10 phosphorylation; and histone H3-T3 phosphorylation. Predicted to act upstream of or within protein autophosphorylation. Predicted to be located in Golgi stack; cytosol; and nuclear lumen. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Vrk1 Products(1)

mRNA Protein Name
NM_001012194.1 NP_001012194.1 serine/threonine-protein kinase VRK1
Protein Preferred Names Protein Names

serine/threonine-protein kinase VRK1

vaccinia related kinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-126542 VRK-IN-1 Inhibitor 99.47% Unkown
HY-158975 VRK1/CK1-IN-1 Inhibitor 98.69% Unkown
HY-RS15702 VRK1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17597 Vrk1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24057 Vrk1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vrk1 NCBI NCBI:7443