1. Gene
  2. Tle1 - TLE family member 1, transcriptional corepressor Gene

Tle1 - TLE family member 1, transcriptional corepressor Gene

Rattus norvegicus
Gene ID: 362533 | Gene type: protein coding

About Tle1

Summary

Predicted to enable chromatin binding activity; identical protein binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of beta-catenin-TCF complex. Predicted to be active in nucleus. Orthologous to human TLE1 (TLE family member 1, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle1 Products(1)

mRNA Protein Name
NM_001173433.1 NP_001166904.1 transducin-like enhancer protein 1
Protein Preferred Names Protein Names

transducin-like enhancer protein 1

transducin like enhancer of split 1

transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

Orthologs Information

Species Symbol Source ID
Homo sapiens Tle1 NCBI NCBI:7088