2. Gene
  3. Impdh1 - inosine monophosphate dehydrogenase 1 Gene

Impdh1 - inosine monophosphate dehydrogenase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IMPD 1; IMPDH 1

Gene ID: 362329 | Gene type: protein coding

About Impdh1

Summary

Predicted to enable DNA binding activity; IMP dehydrogenase activity; and identical protein binding activity. Involved in response to cold and retina development in camera-type eye. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Impdh1 Products(2)

mRNA Protein Name
NM_001108619.1 NP_001102089.1 inosine-5'-monophosphate dehydrogenase 1 isoform 1
NM_001398857.1 NP_001385786.1 inosine-5'-monophosphate dehydrogenase 1 isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
18295529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inosine-5'-monophosphate dehydrogenase 1

IMP (inosine 5'-monophosphate) dehydrogenase 1

IMP (inosine monophosphate) dehydrogenase 1

IMP dehydrogenase 1

inosine 5'-phosphate dehydrogenase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-169296 IMPDH2-IN-4 / Unkown
HY-RS06798 IMPDH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164434 Xanthosine-5'-monophosphate / Unkown
HY-RS17781 Impdh1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24248 Impdh1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Impdh1 NCBI NCBI:3614