DNAJB6 - Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 Gene

About DNAJB6

Summary

Predicted to enable several functions, including ATPase activator activity; chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including intermediate filament organization; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and negative regulation of inclusion body assembly. Predicted to act upstream of or within several processes, including chorion development; labyrinthine layer development; and protein localization to nucleus. Predicted to be located in several cellular components, including Z disc; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1. Orthologous to human DNAJB6 (DnaJ heat shock protein family (HSP40) member B6). [provided by Alliance of Genome Resources, Apr 2022]