Srsf6 - serine and arginine rich splicing factor 6 Gene

Rattus norvegicus

Also known as Sfrs6

Gene ID: 362264 | Gene type: protein coding

About Srsf6

Summary

Predicted to enable mRNA binding activity and pre-mRNA binding activity. Involved in negative regulation of gene expression; negative regulation of type B pancreatic cell apoptotic process; and response to Insulin. Located in nucleus. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to human SRSF6 (serine and arginine rich splicing factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Srsf6 Products(1)

mRNA	Protein	Name
NM_001014185.2	NP_001014207.2	serine/arginine-rich splicing factor 6

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of gene expression	IMP IMP: Inferred from mutant phenotype	23737756	RGD
involved in negative regulation of type B pancreatic cell apoptotic process	IMP IMP: Inferred from mutant phenotype	23737756	RGD
involved in response to insulin	IEP IEP: Inferred from expression pattern	11283022	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/arginine-rich splicing factor 6

pre-mRNA-splicing factor SRP55

splicing factor, arginine/serine-rich 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13797	SRSF6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21053	Srsf6 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27571	Srsf6 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Srsf6	NCBI	NCBI:6431

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