2. Gene
  3. Snta1 - syntrophin, alpha 1 Gene

Snta1 - syntrophin, alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362242 | Gene type: protein coding

About Snta1

Summary

Enables PDZ domain binding activity. Predicted to be involved in several processes, including negative regulation of peptidyl-cysteine S-nitrosylation; regulation of ion transmembrane transport; and ventricular cardiac muscle cell action potential. Predicted to act upstream of or within neuromuscular junction development and regulation of vasoconstriction by circulating norepinephrine. Located in neuromuscular junction and sarcolemma. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 12; and sudden infant death syndrome. Orthologous to human SNTA1 (syntrophin alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Snta1 Products(1)

mRNA Protein Name
NM_001100901.1 NP_001094371.1 alpha-1-syntrophin
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
15024025 RGD
Cellular Component GO Annotation Evidence Reference Source
located in neuromuscular junction IDA
IDA: Inferred from direct assay
7819523 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
7819523 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1-syntrophin

syntrophin, acidic 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13512 SNTA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22813 Snta1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS29328 Snta1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snta1 NCBI NCBI:6640