2. Gene
  3. Xrn2 - 5'-3' exoribonuclease 2 Gene

Xrn2 - 5'-3' exoribonuclease 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362229 | Gene type: protein coding

About Xrn2

Summary

Predicted to enable exoribonuclease activity, producing 5'-phosphomonoesters; identical protein binding activity; and nucleic acid binding activity. Involved in hippocampus development; neuron differentiation; and retina development in camera-type eye. Located in nucleus. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma and lung Cancer. Orthologous to human XRN2 (5'-3' exoribonuclease 2). [provided by Alliance of Genome Resources, Apr 2022]

Xrn2 Products(1)

mRNA Protein Name
NM_001108596.2 NP_001102066.2 5'-3' exoribonuclease 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in hippocampus development IEP
IEP: Inferred from expression pattern
23933240 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
23933240 RGD
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
23700402 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5'-3' exoribonuclease 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15903 XRN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20840 Xrn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27354 Xrn2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xrn2 NCBI NCBI:22803