2. Gene
  3. Setx - senataxin Gene

Setx - senataxin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1565575

Gene ID: 362096 | Gene type: protein coding

About Setx

Summary

Predicted to enable RNA binding activity; identical protein binding activity; and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in several processes, including intracellular signal transduction; nucleic acid metabolic process; and positive regulation of RNA metabolic process. Predicted to act upstream of or within circadian rhythm. Predicted to be located in several cellular components, including growth cone; intercellular bridge; and nuclear lumen. Predicted to be active in nuclear body. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and ataxia with oculomotor apraxia type 2. Orthologous to human SETX (senataxin). [provided by Alliance of Genome Resources, Apr 2022]

Setx Products(4)

mRNA Protein Name
XM_006233887.4 XP_006233949.1 probable helicase senataxin isoform X1
XM_039106151.1 XP_038962079.1 probable helicase senataxin isoform X2
XM_039106152.1 XP_038962080.1 probable helicase senataxin isoform X3
XM_006233886.4 XP_006233948.1 probable helicase senataxin isoform X1
Protein Preferred Names Protein Names

probable helicase senataxin

DEAxQ-box helicase

tRNA splicing endonuclease regulator 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12752 SETX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22320 Setx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28842 Setx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Setx NCBI NCBI:23064