2. Gene
  3. ALDH18A1 - Aldh18a1 aldehyde dehydrogenase 18 family, member A1 Gene

ALDH18A1 - Aldh18a1 aldehyde dehydrogenase 18 family, member A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pycs

Gene ID: 361755 | Gene type: protein coding

About ALDH18A1

Summary

Predicted to enable glutamate 5-kinase activity; glutamate-5-semialdehyde dehydrogenase activity; and identical protein binding activity. Involved in response to temperature stimulus. Located in mitochondrial membrane. Human ortholog(s) of this gene implicated in cataract; cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Orthologous to human ALDH18A1 (aldehyde dehydrogenase 18 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

ALDH18A1 Products(2)

mRNA Protein Name
NM_001108524.2 NP_001101994.1 delta-1-pyrroline-5-carboxylate synthase isoform 1
NM_001395675.1 NP_001382604.1 delta-1-pyrroline-5-carboxylate synthase isoform 2
Protein Preferred Names Protein Names

delta-1-pyrroline-5-carboxylate synthase

pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156443 YG1702 Inhibitor 99.94% Unkown
HY-RS00559 ALDH18A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19101 Aldh18a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25590 Aldh18a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ALDH18A1 NCBI NCBI:5832