2. Gene
  3. Arap3 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Gene

Arap3 - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Centd3; Arap3-ps1; RGD1304938

Gene ID: 361314 | Gene type: protein coding

About Arap3

Summary

Predicted to enable GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in positive regulation of GTPase activity and signal transduction. Predicted to act upstream of or within negative regulation of Ras protein signal transduction; negative regulation of cell migration; and regulation of cell shape. Predicted to be located in cytoplasm and lamellipodium. Predicted to be active in ruffle. Orthologous to human ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Arap3 Products(6)

mRNA Protein Name
XM_039097402.1 XP_038953330.1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1
XM_039097404.1 XP_038953332.1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X2
XM_039097405.1 XP_038953333.1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3
XM_008772073.3 XP_008770295.2 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X4
XM_039097403.1 XP_038953331.1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1
XM_039097406.1 XP_038953334.1 arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X5
Protein Preferred Names Protein Names

arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, pseudogene 1

centaurin, delta 3

dual-specificity Rho- and Arf-GTPase activating protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00889 ARAP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21483 Arap3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28001 Arap3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arap3 NCBI NCBI:64411