2. Gene
  3. Elmo1 - engulfment and cell motility 1 Gene

Elmo1 - engulfment and cell motility 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ELMO1s

Gene ID: 361251 | Gene type: protein coding

About Elmo1

Summary

Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including Rac protein signal transduction; actin filament organization; and phagocytosis, engulfment. Predicted to act upstream of or within actin filament-based process and phagocytosis. Predicted to be located in cytoplasm. Predicted to be part of guanyl-nucleotide exchange factor complex. Predicted to be active in plasma membrane. Orthologous to human ELMO1 (engulfment and cell motility 1). [provided by Alliance of Genome Resources, Apr 2022]

Elmo1 Products(1)

mRNA Protein Name
NM_001395578.1 NP_001382507.1 engulfment and cell motility protein 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
21900250 RGD
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
21900250 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21900250 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21900250 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
21900250 RGD
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
21900250 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

engulfment and cell motility protein 1

engulfment and cell motility 1 splice 1

engulfment and cell motility 1, ced-12 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04311 ELMO1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22485 Elmo1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS29008 Elmo1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elmo1 NCBI NCBI:9844