2. Gene
  3. NGLY1 - Ngly1 N-glycanase 1 Gene

NGLY1 - Ngly1 N-glycanase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 361014 | Gene type: protein coding

About NGLY1

Summary

Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Involved in ER-associated misfolded protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Used to study NGLY1-deficiency. Human ortholog(s) of this gene implicated in NGLY1-deficiency. Orthologous to human NGLY1 (N-glycanase 1). [provided by Alliance of Genome Resources, Apr 2022]

NGLY1 Products(1)

mRNA Protein Name
NM_001014136.1 NP_001014158.1 peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Protein Preferred Names Protein Names

peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

PNGase

peptide:N-glycanase

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-129225 WRR139 Inhibitor 99.71% Unkown
HY-N9446 H-Asn(glcnac-beta-D)-OH 98.65% Unkown
HY-P10135 RES-701-1 Antagonist / Unkown
HY-RS09279 NGLY1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-P2064 Lariatin A Inhibitor / Unkown
HY-RS19221 Ngly1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25710 Ngly1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NGLY1 NCBI NCBI:55768