2. Gene
  3. DOCK2 - Dock2 dedicator of cytokinesis 2 Gene

DOCK2 - Dock2 dedicator of cytokinesis 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AABR07029272.1

Gene ID: 360509 | Gene type: protein coding

About DOCK2

Summary

Predicted to enable GTPase activator activity; T cell receptor binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in macropinocytosis; myeloid dendritic cell activation involved in immune response; and positive regulation of phagocytosis. Predicted to act upstream of or within several processes, including T cell activation; immunological synapse formation; and membrane raft polarization. Human ortholog(s) of this gene implicated in immunodeficiency 40. Orthologous to human DOCK2 (dedicator of cytokinesis 2). [provided by Alliance of Genome Resources, Apr 2022]

DOCK2 Products(5)

mRNA Protein Name
XM_039087139.1 XP_038943067.1 dedicator of cytokinesis protein 2 isoform X1
XM_039087140.1 XP_038943068.1 dedicator of cytokinesis protein 2 isoform X2
XM_039087141.1 XP_038943069.1 dedicator of cytokinesis protein 2 isoform X3
XM_039087143.1 XP_038943071.1 dedicator of cytokinesis protein 2 isoform X5
XM_039087142.1 XP_038943070.1 dedicator of cytokinesis protein 2 isoform X4
Protein Preferred Names Protein Names

dedicator of cytokinesis protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153128 DOCK2-IN-1 Inhibitor 96.20% Unkown
HY-111355 Cholesterol sulfate Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DOCK2 NCBI NCBI:1794