2. Gene
  3. Tbx3 - T-box transcription factor 3 Gene

Tbx3 - T-box transcription factor 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 353305 | Gene type: protein coding

About Tbx3

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of apoptotic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tbx3 Products(1)

mRNA Protein Name
NM_181638.2 NP_853669.1 T-box transcription factor TBX3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15694670 RGD
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18285513 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-box transcription factor TBX3

T-box 3 (ulnar mammary syndrome)

T-box protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14279 TBX3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20344 Tbx3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26853 Tbx3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbx3 NCBI NCBI:6926