2. Gene
  3. Kdm7a - lysine (K)-specific demethylase 7A Gene

Kdm7a - lysine (K)-specific demethylase 7A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Jhdm1d; mKIAA1718; A630082K20Rik

Gene ID: 338523 | Gene type: protein coding

About Kdm7a

Summary

Enables histone H3-methyl-lysine-9 demethylase activity and histone H3-tri/di-methyl-lysine-27 demethylase activity. Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm7a Products(1)

mRNA Protein Name
NM_001033430.4 NP_001028602.2 lysine-specific demethylase 7A
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables histone H3K27me2/H3K27me3 demethylase activity IMP
IMP: Inferred from mutant phenotype
20194436 MGI
enables histone H3K9 demethylase activity IMP
IMP: Inferred from mutant phenotype
20194436 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20194436 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysine-specific demethylase 7A

[histone H3]-dimethyl-L-lysine9 demethylase 7A

jmjC domain-containing histone demethylation protein 1D

jumonji C domain-containing histone demethylase 1 homolog D

lysine-specific demethylase 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107573 KDM2/7-IN-1 Inhibitor 99.00% Unkown
HY-RS07224 KDM7A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19701 Kdm7a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26196 Kdm7a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm7a NCBI NCBI:80853