2. Gene
  3. Fan1 - FANCD2/FANCI-associated nuclease 1 Gene

Fan1 - FANCD2/FANCI-associated nuclease 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mFAN1; Mtmr15; 6030441H18Rik

Gene ID: 330554 | Gene type: protein coding

About Fan1

Summary

Enables 5'-3' exonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination; interstrand cross-link repair; and nucleotide-excision repair, DNA incision. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be active in nucleus. Is expressed in ductus deferens; epididymis; and testis. Used to study karyomegalic interstitial nephritis. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Orthologous to human FAN1 (FANCD2 and FANCI associated nuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Fan1 Products(1)

mRNA Protein Name
NM_177893.4 NP_808561.2 fanconi-associated nuclease 1
Protein Preferred Names Protein Names

fanconi-associated nuclease 1

coiled-coil domain-containing protein MTMR15

myotubularin-related protein 15

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04731 FAN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22166 Fan1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fan1 NCBI NCBI:22909