2. Gene
  3. Myo3b - myosin IIIB Gene

Myo3b - myosin IIIB Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A430065P19Rik

Gene ID: 329421 | Gene type: protein coding

About Myo3b

Summary

Enables microfilament motor activity and protein serine/threonine kinase activity. Involved in auditory receptor cell stereocilium organization; cochlea morphogenesis; and sensory perception of sound. Acts upstream of or within positive regulation of filopodium assembly; protein phosphorylation; and regulation of actin filament length. Located in filopodium tip; photoreceptor inner segment; and photoreceptor outer segment. Is active in stereocilium tip. Is expressed in several structures, including genitourinary system; nervous system; and submandibular gland. Orthologous to human MYO3B (Myosin IIIB). [provided by Alliance of Genome Resources, Apr 2022]

Myo3b Products(1)

mRNA Protein Name
NM_177376.5 NP_796350.2 myosin-IIIb
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables microfilament motor activity IDA
IDA: Inferred from direct assay
22264607 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22264607 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
21895655 MGI
Biological Process GO Annotation Evidence Reference Source
involved in auditory receptor cell stereocilium organization IGI
IGI: Inferred from genetic interaction
26754646 MGI
involved in auditory receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
26754646 MGI
involved in cochlea morphogenesis IMP
IMP: Inferred from mutant phenotype
26754646 MGI
acts upstream of or within peptidyl-serine phosphorylation IDA
IDA: Inferred from direct assay
21895655 MGI
acts upstream of or within peptidyl-threonine phosphorylation IDA
IDA: Inferred from direct assay
21895655 MGI
acts upstream of or within positive regulation of filopodium assembly IPI
IPI: Inferred from physical interaction
22264607 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: Inferred from direct assay
21895655 MGI
involved in regulation of actin filament length IGI
IGI: Inferred from genetic interaction
26754646 MGI
involved in regulation of actin filament length IMP
IMP: Inferred from mutant phenotype
26754646 MGI
involved in sensory perception of sound IGI
IGI: Inferred from genetic interaction
26754646 MGI
involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
26754646 MGI
Cellular Component GO Annotation Evidence Reference Source
located in filopodium tip IPI
IPI: Inferred from physical interaction
22264607 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
19332056 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
19332056 MGI
is active in stereocilium tip EXP
EXP: Inferred from Experiment
26754646 MGI
located in stereocilium tip IDA
IDA: Inferred from direct assay
22264607 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin-IIIb

myosin IIIB1

myosin IIIB2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08945 MYO3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22664 Myo3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29178 Myo3b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo3b NCBI NCBI:140469