2. Gene
  3. Ddx11 - DEAD/H box helicase 11 Gene

Ddx11 - DEAD/H box helicase 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CHL1; KRG2; CHLR1; essa15a; 4732462I11Rik

Gene ID: 320209 | Gene type: protein coding

About Ddx11

Summary

Predicted to enable several functions, including 5'-3' DNA helicase activity; ATP-dependent activity, acting on RNA; and nucleic acid binding activity. Predicted to be involved in DNA duplex unwinding and establishment of sister chromatid cohesion. Predicted to act upstream of or within DNA repair and DNA replication. Predicted to be located in several cellular components, including microtubule cytoskeleton; midbody; and nuclear lumen. Predicted to be part of Ctf18 RFC-like complex. Predicted to be active in nucleus. Is expressed in allantois; embryo; placenta; and yolk sac endoderm. Human ortholog(s) of this gene implicated in Warsaw breakage syndrome. Orthologous to several human genes including DDX11 (DEAD/H-box helicase 11). [provided by Alliance of Genome Resources, Apr 2022]

Ddx11 Products(2)

mRNA Protein Name
NM_001003919.2 NP_001003919.1 ATP-dependent DNA helicase DDX11 isoform 1
NM_001348292.1 NP_001335221.1 ATP-dependent DNA helicase DDX11 isoform 2
Protein Preferred Names Protein Names

ATP-dependent DNA helicase DDX11

DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)

probable ATP-dependent RNA helicase DDX11

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03631 DDX11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21547 Ddx11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28065 Ddx11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddx11 NCBI NCBI:1663