2. Gene
  3. Il1rapl1 - interleukin 1 receptor accessory protein-like 1 Gene

Il1rapl1 - interleukin 1 receptor accessory protein-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Il1rapl

Gene ID: 317553 | Gene type: protein coding

About Il1rapl1

Summary

Predicted to enable signaling receptor binding activity. Involved in negative regulation of exocytosis and regulation of neuron projection development. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 21. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1rapl1 Products(1)

mRNA Protein Name
NM_177935.2 NP_808796.1 interleukin-1 receptor accessory protein-like 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of exocytosis IDA
IDA: Inferred from direct assay
17502602 RGD
involved in regulation of neuron projection development IDA
IDA: Inferred from direct assay
17502602 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20096586 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
20096586 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-1 receptor accessory protein-like 1

IL-1-RAPL-1

IL-1RAPL-1

IL1RAPL-1

X-linked interleukin-1 receptor accessory protein-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06723 IL1RAPL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17932 Il1rapl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24402 Il1rapl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991468 IMM20324 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rapl1 NCBI NCBI:11141
Mus musculus Il1rapl1 NCBI NCBI:331461