Pgap1 - post-GPI attachment to proteins inositol deacylase 1 Gene

Rattus norvegicus

Gene ID: 316400 | Gene type: protein coding

About Pgap1

Summary

Enables phosphatidylinositol deacylase activity. Involved in GPI anchor biosynthetic process and positive regulation of ER to Golgi vesicle-mediated transport. Located in endoplasmic reticulum. Orthologous to human PGAP1 (post-GPI attachment to proteins inositol deacylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pgap1 Products(1)

mRNA	Protein	Name
NM_201990.1	NP_973719.1	GPI inositol-deacylase

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables phosphatidylinositol deacylase activity	IMP IMP: Inferred from mutant phenotype	14734546	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in GPI anchor biosynthetic process	IMP IMP: Inferred from mutant phenotype	14734546	RGD
involved in positive regulation of ER to Golgi vesicle-mediated transport	IMP IMP: Inferred from mutant phenotype	14734546	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	14734546	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

GPI inositol-deacylase

GPI deacylase	Post GPI Attachment to Proteins 1
post-GPI attachment to proteins 1	post-GPI attachment to proteins factor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10377	PGAP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21019	Pgap1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27536	Pgap1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pgap1	NCBI	NCBI:80055

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