2. Gene
  3. Glb1 - galactosidase, beta 1 Gene

Glb1 - galactosidase, beta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 316033 | Gene type: protein coding

About Glb1

Summary

Enables beta-galactosidase activity and galactoside binding activity. Involved in galactose catabolic process; response to Thyroglobulin triiodothyronine; and response to cortisone. Located in lysosome. Human ortholog(s) of this gene implicated in GM1 gangliosidosis (multiple) and mucopolysaccharidosis IV (multiple). Orthologous to human GLB1 (galactosidase beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Glb1 Products(1)

mRNA Protein Name
NM_001108192.2 NP_001101662.1 beta-galactosidase precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables beta-galactosidase activity IDA
IDA: Inferred from direct assay
6811372 RGD
enables beta-galactosidase activity IMP
IMP: Inferred from mutant phenotype
8717430 RGD
enables galactoside binding IDA
IDA: Inferred from direct assay
8702598 RGD
Biological Process GO Annotation Evidence Reference Source
involved in galactose catabolic process IDA
IDA: Inferred from direct assay
6811372 RGD
involved in response to Thyroglobulin triiodothyronine IEP
IEP: Inferred from expression pattern
414795 RGD
involved in response to cortisone IEP
IEP: Inferred from expression pattern
6411136 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-galactosidase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05464 GLB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05465 GLB1L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12839 SH3GLB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18938 Glb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25428 Glb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glb1 NCBI NCBI:2720