2. Gene
  3. FLI1 - Fli1 Fli-1 proto-oncogene, ETS transcription factor Gene

FLI1 - Fli1 Fli-1 proto-oncogene, ETS transcription factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 315532 | Gene type: protein coding

About FLI1

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including blood circulation; megakaryocyte development; and regulation of transcription, DNA-templated. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in blood platelet disease and thrombocytopenia. Orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

FLI1 Products(1)

mRNA Protein Name
NM_001017381.2 NP_001017381.1 Friend leukemia integration 1 transcription factor
Protein Preferred Names Protein Names

Friend leukemia integration 1 transcription factor

Friend leukemia integration 1 transcription factor-like

Friend leukemia virus integration 1

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-122903 TK216 Inhibitor 99.84% Phase 2
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14507 YK-4-279 99.91% Unkown
HY-173364 EB-TCIP Inducer / Unkown
HY-163325 Fli-1-IN-1 fumarate Inhibitor / Unkown
HY-163325A Fli-1-IN-1 Inhibitor / Unkown
HY-RS04581 EWSR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04977 FLI1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04978 FLII Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18357 Fli1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24836 Fli1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FLI1 NCBI NCBI:2313