2. Gene
  3. Jam3 - junctional adhesion molecule 3 Gene

Jam3 - junctional adhesion molecule 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 315509 | Gene type: protein coding

About Jam3

Summary

Predicted to enable cell-cell adhesion mediator activity; identical protein binding activity; and Integrin binding activity. Involved in axon regeneration. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; cell-cell contact zone; and paranodal junction. Predicted to be integral component of plasma membrane. Predicted to be part of filamentous actin and protein complex involved in cell adhesion. Predicted to colocalize with bicellular tight junction. Biomarker of sciatic neuropathy. Orthologous to human JAM3 (junctional adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]

Jam3 Products(1)

mRNA Protein Name
NM_001004269.1 NP_001004269.1 junctional adhesion molecule C precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in axon regeneration IEP
IEP: Inferred from expression pattern
22950044 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

junctional adhesion molecule C

JAM-3

JAM-C

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07028 JAM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19344 Jam3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25835 Jam3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Jam3 NCBI NCBI:83700
Mus musculus Jam3 NCBI NCBI:83964