Tab1 - TGF-beta activated kinase 1/MAP3K7 binding protein 1 Gene

Rattus norvegicus

Also known as Map3k7ip1

Gene ID: 315139 | Gene type: protein coding

About Tab1

Summary

Enables mitogen-activated protein kinase p38 binding activity. Involved in positive regulation of MAP kinase activity. Part of protein-containing complex. Orthologous to human TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tab1 Products(1)

mRNA	Protein	Name
NM_001109976.2	NP_001103446.1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mitogen-activated protein kinase p38 binding	IPI IPI: Inferred from physical interaction	21607062	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	16617054	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	16617054	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of MAP kinase activity	IMP IMP: Inferred from mutant phenotype	21607062	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of protein-containing complex	IDA IDA: Inferred from direct assay	16617054	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Tak1-binding protein 1

mitogen-activated protein kinase kinase kinase 7 interacting protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N2435	[8]-Shogaol		99.93%	Unkown
HY-114454	INH14	Inhibitor	≥98.0%	Unkown
HY-167704	NF023		/	Unkown
HY-RS14133	TAB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19961	Tab1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26463	Tab1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tab1	NCBI	NCBI:10454

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