2. Gene
  3. Asap1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 Gene

Asap1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as DEF-1; Ddef1

Gene ID: 314961 | Gene type: protein coding

About Asap1

Summary

Predicted to enable GTPase activator activity; SH3 domain binding activity; and phospholipid binding activity. Predicted to be involved in cilium assembly; positive regulation of membrane tubulation; and positive regulation of podosome assembly. Predicted to act upstream of or within negative regulation of dendritic spine development. Predicted to be located in dendritic spine. Predicted to be active in cell projection membrane; cytosol; and podosome. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Asap1 Products(1)

mRNA Protein Name
NM_001044245.2 NP_001037710.2 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Protein Preferred Names Protein Names

arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein

130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein

ADP-ribosylation factor-directed GTPase-activating protein 1

ARF GTPase-activat

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01055 ASAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20858 Asap1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27373 Asap1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asap1 NCBI NCBI:50807