2. Gene
  3. Orc1 - origin recognition complex, subunit 1 Gene

Orc1 - origin recognition complex, subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Orc1l

Gene ID: 313479 | Gene type: protein coding

About Orc1

Summary

Enables chromatin binding activity. Involved in positive regulation of G0 to G1 transition and positive regulation of smooth muscle cell proliferation. Located in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Orthologous to human ORC1 (origin recognition complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Orc1 Products(1)

mRNA Protein Name
NM_177931.2 NP_808792.1 origin recognition complex subunit 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
16982680 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of G0 to G1 transition IMP
IMP: Inferred from mutant phenotype
18499104 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
18499104 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

origin recognition complex subunit 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09825 ORC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13095 SLC25A15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20788 Orc1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27302 Orc1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Orc1 NCBI NCBI:4998