2. Gene
  3. USP18 - Usp18 ubiquitin specific peptidase 18 Gene

USP18 - Usp18 ubiquitin specific peptidase 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 312688 | Gene type: protein coding

About USP18

Summary

Predicted to enable ISG15-specific protease activity; cysteine-type endopeptidase activity; and thiol-dependent Deubiquitinase. Predicted to be involved in negative regulation of type I interferon-mediated signaling pathway; protein deubiquitination; and regulation of inflammatory response. Predicted to act upstream of or within response to bacterium and response to stilbenoid. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including USP18 (ubiquitin specific peptidase 18). [provided by Alliance of Genome Resources, Apr 2022]

USP18 Products(1)

mRNA Protein Name
NM_001014058.2 NP_001014080.1 ubl carboxyl-terminal hydrolase 18
Protein Preferred Names Protein Names

ubl carboxyl-terminal hydrolase 18

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111458 GSK2643943A Inhibitor 98.79% Unkown
HY-172969 ZHAWOC8655 Inhibitor 98.63% Unkown
HY-RS15528 USP18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17777 Usp18 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24244 Usp18 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens USP18 NCBI NCBI:11274