Adipor2 - adiponectin receptor 2 Gene

Rattus norvegicus

Gene ID: 312670 | Gene type: protein coding

About Adipor2

Summary

Predicted to enable adipokinetic hormone receptor activity; Adiponectin binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of hepatic stellate cell migration; positive regulation of glucose import; and response to fructose. Predicted to be intrinsic component of plasma membrane. Predicted to be active in plasma membrane. Biomarker of end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); and obesity. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease and type 2 diabetes mellitus. Orthologous to human ADIPOR2 (Adiponectin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Adipor2 Products(1)

mRNA	Protein	Name
NM_001037979.1	NP_001033068.1	adiponectin receptor protein 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to fatty acid	IEP IEP: Inferred from expression pattern	21194380	RGD
involved in female pregnancy	IEP IEP: Inferred from expression pattern	15855268	RGD
involved in heart development	IEP IEP: Inferred from expression pattern	15754086	RGD
involved in negative regulation of cell growth	IMP IMP: Inferred from mutant phenotype	16415076	RGD
involved in negative regulation of gene expression	IMP IMP: Inferred from mutant phenotype	29237572	RGD
involved in negative regulation of hepatic stellate cell migration	IMP IMP: Inferred from mutant phenotype	29237572	RGD
involved in positive regulation of D-glucose import	IMP IMP: Inferred from mutant phenotype	17569760	RGD
involved in positive regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	29237572	RGD
involved in response to amine	IEP IEP: Inferred from expression pattern	17696487	RGD
involved in response to bacterium	IEP IEP: Inferred from expression pattern	23797890	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	23838384	RGD
involved in response to fructose	IEP IEP: Inferred from expression pattern	23797890	RGD
involved in response to lipopolysaccharide	IEP IEP: Inferred from expression pattern	23838384	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	16483885	RGD
involved in response to nutrient levels	IEP IEP: Inferred from expression pattern	17006986	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	26115886	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

adiponectin receptor protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15848	AdipoRon	Agonist	99.88%	Unkown
HY-N0166	Gramine		99.80%	Unkown
HY-110164	AdipoRon hydrochloride	Agonist	/	Unkown
HY-N0166R	Gramine (Standard)		/	Unkown
HY-RS00380	ADIPOR2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21981	Adipor2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28498	Adipor2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adipor2	NCBI	NCBI:79602

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