2. Gene
  3. Tia1 - TIA1 cytotoxic granule-associated RNA binding protein Gene

Tia1 - TIA1 cytotoxic granule-associated RNA binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 312510 | Gene type: protein coding

About Tia1

Summary

Predicted to enable mRNA 3'-UTR AU-rich region binding activity. Involved in positive regulation of epithelial cell apoptotic process. Located in cytoplasmic stress granule and nucleus. Part of ribonucleoprotein complex. Biomarker of transient cerebral ischemia. Orthologous to human TIA1 (TIA1 cytotoxic granule associated RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tia1 Products(1)

mRNA Protein Name
NM_001012096.1 NP_001012096.1 nucleolysin TIA-1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22555848 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
16055272 RGD
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
12855701 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleolysin TIA-1

cytotoxic granule-associated RNA binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14513 TIA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20825 Tia1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27339 Tia1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tia1 NCBI NCBI:7072