2. Gene
  3. Dysf - dysferlin Gene

Dysf - dysferlin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 312492 | Gene type: protein coding

About Dysf

Summary

Predicted to enable calcium ion binding activity; calcium-dependent phospholipid binding activity; and tubulin binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; negative regulation of phagocytosis; and plasma membrane organization. Predicted to act upstream of or within several processes, including negative regulation of macromolecule metabolic process; positive regulation of neutrophil chemotaxis; and regulation of calcium ion transport. Located in cytoplasm. Human ortholog(s) of this gene implicated in Miyoshi muscular dystrophy 1; autosomal recessive limb-girdle muscular dystrophy type 2B; distal muscular dystrophy with anterior tibial onset; and muscular dystrophy. Orthologous to human DYSF (dysferlin). [provided by Alliance of Genome Resources, Apr 2022]

Dysf Products(1)

mRNA Protein Name
NM_001107869.1 NP_001101339.1 dysferlin
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17185750 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dysferlin

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04105 DYSF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20722 Dysf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27234 Dysf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dysf NCBI NCBI:8291