2. Gene
  3. Tmem106b - transmembrane protein 106B Gene

Tmem106b - transmembrane protein 106B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as LRRGT00101

Gene ID: 312132 | Gene type: protein coding

About Tmem106b

Summary

Predicted to enable ATPase binding activity. Predicted to be involved in several processes, including dendrite morphogenesis; lysosome localization; and lysosome organization. Predicted to act upstream of or within several processes, including lysosomal lumen acidification; lysosomal protein catabolic process; and positive regulation of dendrite development. Predicted to be located in endosome and lysosome. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human TMEM106B (transmembrane protein 106B). [provided by Alliance of Genome Resources, Apr 2022]

Tmem106b Products(1)

mRNA Protein Name
NM_001004267.1 NP_001004267.1 transmembrane protein 106B
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24357581 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 106B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14646 TMEM106B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20232 Tmem106b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26739 Tmem106b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem106b NCBI NCBI:54664
Mus musculus Tmem106b NCBI NCBI:71900