2. Gene
  3. Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1306534

Gene ID: 311647 | Gene type: protein coding

About Prex1

Summary

Predicted to enable phospholipid binding activity. Involved in positive regulation of cell migration; regulation of actin filament polymerization; and regulation of dendrite development. Located in several cellular components, including dendritic shaft; growth cone; and perinuclear region of cytoplasm. Orthologous to human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Prex1 Products(1)

mRNA Protein Name
NM_001135718.2 NP_001129190.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cell migration IMP
IMP: Inferred from mutant phenotype
15858067 RGD
involved in regulation of actin filament polymerization IMP
IMP: Inferred from mutant phenotype
18697831 RGD
involved in regulation of dendrite development IMP
IMP: Inferred from mutant phenotype
18697831 RGD
Cellular Component GO Annotation Evidence Reference Source
located in dendritic shaft IDA
IDA: Inferred from direct assay
18697831 RGD
located in growth cone IDA
IDA: Inferred from direct assay
18697831 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18697831 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104064 1A-116 99.72% Unkown
HY-RS11085 PREX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21697 Prex1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28215 Prex1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prex1 NCBI NCBI:57580