2. Gene
  3. Pofut1 - protein O-fucosyltransferase 1 Gene

Pofut1 - protein O-fucosyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fut12; O-FucT-1

Gene ID: 311551 | Gene type: protein coding

About Pofut1

Summary

Predicted to enable peptide-O-fucosyltransferase activity. Predicted to be involved in protein O-linked fucosylation and regulation of Notch signaling pathway. Predicted to act upstream of or within several processes, including Notch signaling pathway; circulatory system development; and somitogenesis. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pofut1 Products(1)

mRNA Protein Name
NM_001002278.2 NP_001002278.1 GDP-fucose protein O-fucosyltransferase 1 precursor
Protein Preferred Names Protein Names

GDP-fucose protein O-fucosyltransferase 1

peptide-O-fucosyltransferase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70160 Protein O-Fucosyltransferase 1 / Unkown
HY-RS10811 POFUT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20191 Pofut1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26695 Pofut1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pofut1 NCBI NCBI:23509