2. Gene
  3. Itpa - inosine triphosphatase Gene

Itpa - inosine triphosphatase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 311422 | Gene type: protein coding

About Itpa

Summary

Predicted to enable dITP diphosphatase activity and identical protein binding activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to act upstream of or within ITP catabolic process and chromosome organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); developmental and epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Itpa Products(1)

mRNA Protein Name
NM_001107774.1 NP_001101244.1 inosine triphosphate pyrophosphatase
Protein Preferred Names Protein Names

inosine triphosphate pyrophosphatase

ITPase

NTPase

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

non-canonical purine NTP pyrophosphatase

non-standard purine NTP pyrophosphatase

nucleoside-triphosphate diphosphatase

nucleoside-triphosphate pyrophosphatase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16965 TH287 Inhibitor 98.29% Unkown
HY-RS06986 ITPA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-16965A TH287 hydrochloride Inhibitor / Unkown
HY-RS20758 Itpa Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27271 Itpa Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itpa NCBI NCBI:3704