2. Gene
  3. Sgms2 - sphingomyelin synthase 2 Gene

Sgms2 - sphingomyelin synthase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as spermatin; RGD1305778

Gene ID: 310849 | Gene type: protein coding

About Sgms2

Summary

Predicted to enable ceramide cholinephosphotransferase activity; ceramide phosphoethanolamine synthase activity; and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process; regulation of bone mineralization; and sphingomyelin biosynthetic process. Predicted to act upstream of or within ceramide phosphoethanolamine biosynthetic process. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to human SGMS2 (sphingomyelin synthase 2). [provided by Alliance of Genome Resources, Apr 2022]

Sgms2 Products(1)

mRNA Protein Name
NM_001014043.1 NP_001014065.1 phosphatidylcholine:ceramide cholinephosphotransferase 2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
17210739 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylcholine:ceramide cholinephosphotransferase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12806 SGMS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19237 Sgms2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25726 Sgms2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgms2 NCBI NCBI:166929