2. Gene
  3. Sfrp2 - secreted frizzled-related protein 2 Gene

Sfrp2 - secreted frizzled-related protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 310552 | Gene type: protein coding

About Sfrp2

Summary

Predicted to enable several functions, including Wnt-protein binding activity; fibronectin binding activity; and signaling receptor binding activity. Involved in negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and response to nutrient. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular space. Biomarker of myocardial infarction. Orthologous to human SFRP2 (secreted Frizzled related protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp2 Products(1)

mRNA Protein Name
NM_001100700.1 NP_001094170.1 secreted frizzled-related protein 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
24080158 RGD
involved in positive regulation of canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
24080158 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
17341692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

secreted frizzled-related protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12775 SFRP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17992 Sfrp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24463 Sfrp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sfrp2 NCBI NCBI:6423
Macaca fascicularis Sfrp2 NCBI NCBI:102147309
Mus musculus Sfrp2 NCBI NCBI:20319