2. Gene
  3. Ercc8 - ERCC excision repair 8, CSA ubiquitin ligase complex subunit Gene

Ercc8 - ERCC excision repair 8, CSA ubiquitin ligase complex subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ckn1

Gene ID: 310071 | Gene type: protein coding

About Ercc8

Summary

Predicted to contribute to ubiquitin-protein transferase activity. Involved in response to auditory stimulus and response to organic cyclic compound. Located in cytoplasm; nucleus; and perikaryon. Human ortholog(s) of this gene implicated in Cockayne syndrome; Cockayne syndrome A; and UV-sensitive syndrome. Orthologous to human ERCC8 (ERCC excision repair 8, CSA ubiquitin Ligase complex subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ercc8 Products(1)

mRNA Protein Name
NM_001107650.2 NP_001101120.2 DNA excision repair protein ERCC-8
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to auditory stimulus IEP
IEP: Inferred from expression pattern
23022597 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22900489 RGD
Cellular Component GO Annotation Evidence Reference Source
located in perikaryon IDA
IDA: Inferred from direct assay
22900489 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA excision repair protein ERCC-8

Cockayne syndrome 1 (classical)

excision repair cross-complementation group 8

excision repair cross-complementing rodent repair deficiency, complementation group 8

excision repaiross-complementing rodent repair deficiency, complementation group 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04486 ERCC8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22492 Ercc8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS29015 Ercc8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ercc8 NCBI NCBI:1161