2. Gene
  3. Mef2a - myocyte enhancer factor 2a Gene

Mef2a - myocyte enhancer factor 2a Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 309957 | Gene type: protein coding

About Mef2a

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to glucose stimulus; and dendrite morphogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A). [provided by Alliance of Genome Resources, Apr 2022]

Mef2a Products(1)

mRNA Protein Name
NM_001014035.2 NP_001014057.1 myocyte-specific enhancer factor 2A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
10521511 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10521511 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to calcium ion IDA
IDA: Inferred from direct assay
10521511 RGD
involved in cellular response to glucose stimulus IEP
IEP: Inferred from expression pattern
18413674 RGD
involved in dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
16484498 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
17696759 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10521511 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
26240138 RGD
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
17696759 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myocyte-specific enhancer factor 2A

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08309 MEF2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19713 Mef2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26209 Mef2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mef2a NCBI NCBI:4205