2. Gene
  3. Usp25 - ubiquitin specific peptidase 25 Gene

Usp25 - ubiquitin specific peptidase 25 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 30940 | Gene type: protein coding

About Usp25

Summary

Predicted to enable SUMO binding activity; cysteine-type peptidase activity; and enzyme binding activity. Involved in several processes, including interleukin-17-mediated signaling pathway; intracellular signal transduction; and mRNA metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of Proteasome complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; musculature; nervous system; and sensory organ. Orthologous to human USP25 (ubiquitin specific peptidase 25). [provided by Alliance of Genome Resources, Apr 2022]

Usp25 Products(1)

mRNA Protein Name
NM_013918.2 NP_038946.2 ubiquitin carboxyl-terminal hydrolase 25
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in I-kappaB phosphorylation IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in chemokine production IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in cytokine production IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in immune response IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in interleukin-17-mediated signaling pathway IDA
IDA: Inferred from direct assay
23042150 MGI
involved in interleukin-17-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in mRNA metabolic process IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in response to oxidative stress IMP
IMP: Inferred from mutant phenotype
23453926 MGI
involved in stress-activated protein kinase signaling cascade IMP
IMP: Inferred from mutant phenotype
23042150 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 25

deubiquitinating enzyme 25

mUSP25

ubiquitin specific protease 25

ubiquitin thioesterase 25

ubiquitin thiolesterase 25

ubiquitin-specific-processing protease 25

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-117370 USP25/28 inhibitor AZ1 Inhibitor ≥98.0% Unkown
HY-138698 FT206 Inhibitor 98.40% Unkown
HY-153996 CT1113 Inhibitor 99.61% Unkown
HY-RS15535 USP25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17150 Usp25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23599 Usp25 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp25 NCBI NCBI:29761