2. Gene
  3. Lama2 - laminin subunit alpha 2 Gene

Lama2 - laminin subunit alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 309368 | Gene type: protein coding

About Lama2

Summary

Predicted to be an extracellular matrix structural constituent. Involved in Schwann cell differentiation. Located in basement membrane and dendritic spine. Biomarker of renovascular hypertension. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Orthologous to human LAMA2 (laminin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Lama2 Products(2)

mRNA Protein Name
XM_039098968.1 XP_038954896.1 laminin subunit alpha-2 isoform X1
XM_039098969.1 XP_038954897.1 laminin subunit alpha-2 isoform X2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in Schwann cell differentiation IEP
IEP: Inferred from expression pattern
11869039 RGD
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
11271373 RGD
located in dendritic spine IDA
IDA: Inferred from direct assay
9295190 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit alpha-2

laminin, alpha 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07498 LAMA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20977 Lama2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27494 Lama2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lama2 NCBI NCBI:3908