2. Gene
  3. GLDC - Gldc glycine decarboxylase Gene

GLDC - Gldc glycine decarboxylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 309312 | Gene type: protein coding

About GLDC

Summary

Enables anion binding activity; enzyme binding activity; and glycine dehydrogenase (decarboxylating) activity. Involved in glycine decarboxylation via glycine cleavage system and protein-containing complex assembly. Located in mitochondrion. Part of glycine cleavage complex. Human ortholog(s) of this gene implicated in glycine encephalopathy. Orthologous to human GLDC (glycine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

GLDC Products(1)

mRNA Protein Name
NM_001107583.1 NP_001101053.1 glycine dehydrogenase (decarboxylating), mitochondrial
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
6778858 RGD
enables glycine binding IDA
IDA: Inferred from direct assay
6778858 RGD
enables glycine dehydrogenase (decarboxylating) activity IDA
IDA: Inferred from direct assay
6778858 RGD
enables pyridoxal phosphate binding IDA
IDA: Inferred from direct assay
6778858 RGD
Biological Process GO Annotation Evidence Reference Source
involved in glycine decarboxylation via glycine cleavage system IDA
IDA: Inferred from direct assay
6778858 RGD
involved in protein-containing complex assembly IDA
IDA: Inferred from direct assay
6778858 RGD
Cellular Component GO Annotation Evidence Reference Source
part of glycine cleavage complex IDA
IDA: Inferred from direct assay
6778858 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine dehydrogenase (decarboxylating), mitochondrial

glycine decarboxylase, glycine cleavage system protein P)

glycine dehydrogenase (decarboxylating)

glycine dehydrogenase (decarboxylating), mitochondrial-like

glycine dehydrogenase (decarboxylating

glycine decarboxylase, glycine cleavage system protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05468 GLDC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20278 Gldc Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26786 Gldc Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GLDC NCBI NCBI:2731