1. Gene
  2. Itgal - integrin subunit alpha L Gene

Itgal - integrin subunit alpha L Gene

Rattus norvegicus

Also known as LFA-1

Gene ID: 308995 | Gene type: protein coding

About Itgal

Summary

Predicted to enable ICAM-3 receptor activity and cell adhesion molecule binding activity. Involved in cell-cell adhesion. Located in cell surface. Used to study nephritis. Orthologous to human ITGAL (Integrin subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Itgal Products(1)

mRNA Protein Name
NM_001033998.2 NP_001029170.1 integrin alpha-L precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
1672643 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8938183 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
8938183 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-L

integrin, alpha L

lymphocyte function-associated antigen-1

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgal NCBI NCBI:3683
Mus musculus Itgal NCBI NCBI:16408