Smpd1 - sphingomyelin phosphodiesterase 1 Gene

Rattus norvegicus

Gene ID: 308909 | Gene type: protein coding

About Smpd1

Summary

Predicted to enable acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in several processes, including ceramide biosynthetic process; positive regulation of apoptotic process; and response to cocaine. Located in extracellular space and lamellar body. Used to study Wilson disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease; Niemann-Pick disease type A; and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022]

Smpd1 Products(1)

mRNA	Protein	Name
NM_001006997.1	NP_001006998.1	sphingomyelin phosphodiesterase

Protein Preferred Names

Protein Names

sphingomyelin phosphodiesterase

sphingomyelin phosphodiesterase 1, acid lysosomal

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13447	SMPD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17994	Smpd1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24465	Smpd1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Smpd1	NCBI	NCBI:6609
Mus musculus	Smpd1	NCBI	NCBI:20597

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